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TNFα Promotes Th17 Cell Differentiation through IL-6 and IL-1β Produced by Monocytes in Rheumatoid Arthritis

TNFα plays an important role in autoimmune pathogenesis and is the main therapeutic target of rheumatoid arthritis. However, its underlying mechanism is not completely understood. In this study, we described that Th17 cells were accumulated in synovial fluid, which was attributable to TNFα aberrantl...

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Detalles Bibliográficos
Autores principales: Zheng, Yingxia, Sun, Lei, Jiang, Ting, Zhang, Dongqing, He, Dongyi, Nie, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243768/
https://www.ncbi.nlm.nih.gov/pubmed/25436214
http://dx.doi.org/10.1155/2014/385352