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TNFα Promotes Th17 Cell Differentiation through IL-6 and IL-1β Produced by Monocytes in Rheumatoid Arthritis
TNFα plays an important role in autoimmune pathogenesis and is the main therapeutic target of rheumatoid arthritis. However, its underlying mechanism is not completely understood. In this study, we described that Th17 cells were accumulated in synovial fluid, which was attributable to TNFα aberrantl...
Autores principales: | Zheng, Yingxia, Sun, Lei, Jiang, Ting, Zhang, Dongqing, He, Dongyi, Nie, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243768/ https://www.ncbi.nlm.nih.gov/pubmed/25436214 http://dx.doi.org/10.1155/2014/385352 |
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