Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection

BACKGROUND: The inflammasome is an intracellular protein complex triggered by exposure to intracellular pathogens, its components or other endogenous proteins. It leads to the activation of and subsequent release of proinflammatory cytokines such as IL-1β and IL-18. S. Typhimurium is a Gram-negative...

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Detalles Bibliográficos
Autores principales: De Jong, Hanna K, Koh, Gavin CKW, van Lieshout, Miriam HP, Roelofs, Joris JTH, van Dissel, Jaap T, van der Poll, Tom, Wiersinga, W Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243774/
https://www.ncbi.nlm.nih.gov/pubmed/25115174
http://dx.doi.org/10.1186/s12865-014-0030-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243774/
https://www.ncbi.nlm.nih.gov/pubmed/25115174
http://dx.doi.org/10.1186/s12865-014-0030-7

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