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Effects of boceprevir and telaprevir on the pharmacokinetics of dolutegravir

AIMS: The aim was to evaluate the effect of boceprevir and telaprevir on dolutegravir pharmacokinetics (PK); the effect of dolutegravir on boceprevir and telaprevir PK was assessed through comparison with historical data for each hepatitis C virus (HCV) drug's prescribing information alone. MET...

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Detalles Bibliográficos
Autores principales: Johnson, Mark, Borland, Julie, Chen, Shuguang, Savina, Paul, Wynne, Brian, Piscitelli, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243878/
https://www.ncbi.nlm.nih.gov/pubmed/24838177
http://dx.doi.org/10.1111/bcp.12428