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Improved prediction of tacrolimus concentrations early after kidney transplantation using theory-based pharmacokinetic modelling
AIMS: The aim was to develop a theory-based population pharmacokinetic model of tacrolimus in adult kidney transplant recipients and to externally evaluate this model and two previous empirical models. METHODS: Data were obtained from 242 patients with 3100 tacrolimus whole blood concentrations. Ext...
Autores principales: | Størset, Elisabet, Holford, Nick, Hennig, Stefanie, Bergmann, Troels K, Bergan, Stein, Bremer, Sara, Åsberg, Anders, Midtvedt, Karsten, Staatz, Christine E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243902/ https://www.ncbi.nlm.nih.gov/pubmed/25279405 http://dx.doi.org/10.1111/bcp.12361 |
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