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Improvement of Dscam homophilic binding affinity throughout Drosophila evolution
BACKGROUND: Drosophila Dscam1 is a cell-surface protein that plays important roles in neural development and axon tiling of neurons. It is known that thousands of isoforms bind themselves through specific homophilic interactions, a process which provides the basis for cellular self-recognition. Deta...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243935/ https://www.ncbi.nlm.nih.gov/pubmed/25158691 http://dx.doi.org/10.1186/s12862-014-0186-z |