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Improvement of Dscam homophilic binding affinity throughout Drosophila evolution

BACKGROUND: Drosophila Dscam1 is a cell-surface protein that plays important roles in neural development and axon tiling of neurons. It is known that thousands of isoforms bind themselves through specific homophilic interactions, a process which provides the basis for cellular self-recognition. Deta...

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Detalles Bibliográficos
Autores principales: Wang, Guang-Zhong, Marini, Simone, Ma, Xinyun, Yang, Qiang, Zhang, Xuegong, Zhu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243935/
https://www.ncbi.nlm.nih.gov/pubmed/25158691
http://dx.doi.org/10.1186/s12862-014-0186-z