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Deleting multiple lytic genes enhances biomass yield and production of recombinant proteins by Bacillus subtilis

BACKGROUND: Bacillus subtilis is widely used in agriculture and industrial biotechnology; however, cell autolysis significantly decreases its yield in liquid cultures. Numerous factors mediate the lysis of B. subtilis, such as cannibalism factors, prophages, and peptidoglycan (PG) hydrolases. The ai...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Chen, Zhenmin, Zhao, Ruili, Jin, Tingting, Zhang, Xiaoming, Chen, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243946/
https://www.ncbi.nlm.nih.gov/pubmed/25176138
http://dx.doi.org/10.1186/s12934-014-0129-9