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Deleting multiple lytic genes enhances biomass yield and production of recombinant proteins by Bacillus subtilis
BACKGROUND: Bacillus subtilis is widely used in agriculture and industrial biotechnology; however, cell autolysis significantly decreases its yield in liquid cultures. Numerous factors mediate the lysis of B. subtilis, such as cannibalism factors, prophages, and peptidoglycan (PG) hydrolases. The ai...
Autores principales: | Wang, Yi, Chen, Zhenmin, Zhao, Ruili, Jin, Tingting, Zhang, Xiaoming, Chen, Xiangdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243946/ https://www.ncbi.nlm.nih.gov/pubmed/25176138 http://dx.doi.org/10.1186/s12934-014-0129-9 |
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