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Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits
INTRODUCTION: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) represents the most common hereditary form of cerebral small vessel disease characterized by early-onset stroke and premature dementia. It is caused by mutations in the transmembrane re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243959/ https://www.ncbi.nlm.nih.gov/pubmed/25190493 http://dx.doi.org/10.1186/s40478-014-0096-8 |