A high-resolution structure of the EF-hand domain of human polycystin-2

Autosomal dominant polycystic kidney disease (ADPKD) affects over 1:1000 of the worldwide population and is caused by mutations in two genes, PKD1 and PKD2. PKD2 encodes a 968-amino acid membrane spanning protein, Polycystin-2 (PC-2), which is a member of the TRP ion channel family. The C-terminal c...

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Detalles Bibliográficos
Autores principales: Allen, Mark D, Qamar, Seema, Vadivelu, Murali K, Sandford, Richard N, Bycroft, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244000/
https://www.ncbi.nlm.nih.gov/pubmed/24990821
http://dx.doi.org/10.1002/pro.2513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244000/
https://www.ncbi.nlm.nih.gov/pubmed/24990821
http://dx.doi.org/10.1002/pro.2513

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