Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK(1/2) and cell proliferation via Gαq-mediated mechanism

Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling. Emerging data suggest that the cardiovascular system is the main target of apelin, which exerts...

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Detalles Bibliográficos
Autores principales: Bai, Bo, Cai, Xin, Jiang, Yunlu, Karteris, Emmanouil, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244021/
https://www.ncbi.nlm.nih.gov/pubmed/25164432
http://dx.doi.org/10.1111/jcmm.12404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244021/
https://www.ncbi.nlm.nih.gov/pubmed/25164432
http://dx.doi.org/10.1111/jcmm.12404

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