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Analysis of Occludin Trafficking, Demonstrating Continuous Endocytosis, Degradation, Recycling and Biosynthetic Secretory Trafficking

Tight junctions (TJs) link adjacent cells and are critical for maintenance of apical-basolateral polarity in epithelial monolayers. The TJ protein occludin functions in disparate processes, including wound healing and Hepatitis C Virus infection. Little is known about steady-state occludin trafficki...

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Detalles Bibliográficos
Autores principales: Fletcher, Sarah J., Iqbal, Mudassar, Jabbari, Sara, Stekel, Dov, Rappoport, Joshua Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244031/
https://www.ncbi.nlm.nih.gov/pubmed/25422932
http://dx.doi.org/10.1371/journal.pone.0111176