Evaluation of Anti-HIF and Anti-Angiogenic Properties of Honokiol for the Treatment of Ocular Neovascular Diseases

Pathological activation of the hypoxia-inducible-factor (HIF) pathway leading to expression of pro-angiogenic genes, such as vascular endothelial growth factor (VEGF), is the fundamental cause of neovascularization in ocular ischemic diseases and cancers. We have shown that pure honokiol inhibits th...

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Detalles Bibliográficos
Autores principales: Vavilala, Divya Teja, Ponnaluri, V. K. Chaithanya, Kanjilal, Debolina, Mukherji, Mridul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244131/
https://www.ncbi.nlm.nih.gov/pubmed/25422886
http://dx.doi.org/10.1371/journal.pone.0113717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244131/
https://www.ncbi.nlm.nih.gov/pubmed/25422886
http://dx.doi.org/10.1371/journal.pone.0113717

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