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Evaluation of Anti-HIF and Anti-Angiogenic Properties of Honokiol for the Treatment of Ocular Neovascular Diseases

Pathological activation of the hypoxia-inducible-factor (HIF) pathway leading to expression of pro-angiogenic genes, such as vascular endothelial growth factor (VEGF), is the fundamental cause of neovascularization in ocular ischemic diseases and cancers. We have shown that pure honokiol inhibits th...

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Detalles Bibliográficos
Autores principales:	Vavilala, Divya Teja, Ponnaluri, V. K. Chaithanya, Kanjilal, Debolina, Mukherji, Mridul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244131/ https://www.ncbi.nlm.nih.gov/pubmed/25422886 http://dx.doi.org/10.1371/journal.pone.0113717

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