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Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of...

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Detalles Bibliográficos
Autores principales: Shpyleva, Svitlana, Ivanovsky, Samuil, de Conti, Aline, Melnyk, Stepan, Tryndyak, Volodymyr, Beland, Frederick A., James, S. Jill, Pogribny, Igor P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244134/
https://www.ncbi.nlm.nih.gov/pubmed/25423485
http://dx.doi.org/10.1371/journal.pone.0113712