Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects

The methylation status of DNA methylation regions (DMRs) of the imprinted gene IGF2/Igf2 is associated with neural tube defects (NTDs), which are caused by a failure of the neural tube to fold and close and are the second-most common birth defect; however, the characterization of the expression leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Baoling, Zhang, Qin, Liu, Xiaozhen, Miao, Chunyue, Shangguan, Shaofang, Bao, Yihua, Guo, Jin, Wang, Li, Zhang, Ting, Li, Huili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244157/
https://www.ncbi.nlm.nih.gov/pubmed/25423083
http://dx.doi.org/10.1371/journal.pone.0113308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244157/
https://www.ncbi.nlm.nih.gov/pubmed/25423083
http://dx.doi.org/10.1371/journal.pone.0113308

Ejemplares similares