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CONSTRICTOR: Constraint Modification Provides Insight into Design of Biochemical Networks

Advances in computational methods that allow for exploration of the combinatorial mutation space are needed to realize the potential of synthetic biology based strain engineering efforts. Here, we present Constrictor, a computational framework that uses flux balance analysis (FBA) to analyze inhibit...

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Detalles Bibliográficos
Autores principales: Erickson, Keesha E., Gill, Ryan T., Chatterjee, Anushree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244162/
https://www.ncbi.nlm.nih.gov/pubmed/25422896
http://dx.doi.org/10.1371/journal.pone.0113820