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CONSTRICTOR: Constraint Modification Provides Insight into Design of Biochemical Networks
Advances in computational methods that allow for exploration of the combinatorial mutation space are needed to realize the potential of synthetic biology based strain engineering efforts. Here, we present Constrictor, a computational framework that uses flux balance analysis (FBA) to analyze inhibit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244162/ https://www.ncbi.nlm.nih.gov/pubmed/25422896 http://dx.doi.org/10.1371/journal.pone.0113820 |