GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells

Trinucleotide repeats can be highly unstable, mutating far more frequently than point mutations. Repeats typically mutate by addition or loss of units of the repeat. CAG repeat expansions in humans trigger neurological diseases that include myotonic dystrophy, Huntington disease, and several spinoce...

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Detalles Bibliográficos
Autores principales: Santillan, Beatriz A., Moye, Christopher, Mittelman, David, Wilson, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244167/
https://www.ncbi.nlm.nih.gov/pubmed/25423602
http://dx.doi.org/10.1371/journal.pone.0113952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244167/
https://www.ncbi.nlm.nih.gov/pubmed/25423602
http://dx.doi.org/10.1371/journal.pone.0113952

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