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Cytoskeletal confinement of CX(3)CL1 limits its susceptibility to proteolytic cleavage by ADAM10
CX(3)CL1 is a unique chemokine that acts both as a transmembrane endothelial adhesion molecule and, upon proteolytic cleavage, a soluble chemoattractant for circulating leukocytes. The constitutive release of soluble CX(3)CL1 requires the interaction of its transmembrane species with the integral me...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244198/ https://www.ncbi.nlm.nih.gov/pubmed/25253723 http://dx.doi.org/10.1091/mbc.E13-11-0633 |