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csi2p modulates microtubule dynamics and organizes the bipolar spindle for chromosome segregation

Proper chromosome segregation is of paramount importance for proper genetic inheritance. Defects in chromosome segregation can lead to aneuploidy, which is a hallmark of cancer cells. Eukaryotic chromosome segregation is accomplished by the bipolar spindle. Additional mechanisms, such as the spindle...

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Detalles Bibliográficos
Autores principales: Costa, Judite, Fu, Chuanhai, Khare, V. Mohini, Tran, Phong T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244199/
https://www.ncbi.nlm.nih.gov/pubmed/25253718
http://dx.doi.org/10.1091/mbc.E14-09-1370