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Membrane tethering by the atlastin GTPase depends on GTP hydrolysis but not on forming the cross-over configuration
The membrane-anchored atlastin GTPase couples nucleotide hydrolysis to the catalysis of homotypic membrane fusion to form a branched endoplasmic reticulum network. Trans dimerization between atlastins anchored in opposing membranes, accompanied by a cross-over conformational change, is thought to dr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244202/ https://www.ncbi.nlm.nih.gov/pubmed/25253720 http://dx.doi.org/10.1091/mbc.E14-08-1284 |