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TOR complex 2–Ypk1 signaling regulates actin polarization via reactive oxygen species

The evolutionarily conserved mTOR complex 2 (mTORC2) signaling pathway is an important regulator of actin cytoskeletal architecture and, as such, is a candidate target for preventing cancer cell motility and invasion. Remarkably, the precise mechanism(s) by which mTORC2 regulates the actin cytoskele...

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Detalles Bibliográficos
Autores principales: Niles, Brad J., Powers, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244204/
https://www.ncbi.nlm.nih.gov/pubmed/25253719
http://dx.doi.org/10.1091/mbc.E14-06-1122