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TOR complex 2–Ypk1 signaling regulates actin polarization via reactive oxygen species
The evolutionarily conserved mTOR complex 2 (mTORC2) signaling pathway is an important regulator of actin cytoskeletal architecture and, as such, is a candidate target for preventing cancer cell motility and invasion. Remarkably, the precise mechanism(s) by which mTORC2 regulates the actin cytoskele...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244204/ https://www.ncbi.nlm.nih.gov/pubmed/25253719 http://dx.doi.org/10.1091/mbc.E14-06-1122 |