Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia

Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagnostic, prognostic markers and therapeutic targets. However, predicting the functional effect of these genetic alterations beyond affected genes and their...

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Detalles Bibliográficos
Autores principales: Hajingabo, Leon Juvenal, Daakour, Sarah, Martin, Maud, Grausenburger, Reinhard, Panzer-Grümayer, Renate, Dequiedt, Franck, Simonis, Nicolas, Twizere, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244205/
https://www.ncbi.nlm.nih.gov/pubmed/25273558
http://dx.doi.org/10.1091/mbc.E14-06-1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244205/
https://www.ncbi.nlm.nih.gov/pubmed/25273558
http://dx.doi.org/10.1091/mbc.E14-06-1038

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