Growth hormone signaling is necessary for lifespan extension by dietary methionine

Growth hormone significantly impacts lifespan in mammals. Mouse longevity is extended when growth hormone (GH) signaling is interrupted but markedly shortened with high-plasma hormone levels. Methionine metabolism is enhanced in growth hormone deficiency, for example, in the Ames dwarf, but suppress...

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Detalles Bibliográficos
Autores principales: Brown-Borg, Holly M, Rakoczy, Sharlene G, Wonderlich, Joseph A, Rojanathammanee, Lalida, Kopchick, John J, Armstrong, Vanessa, Raasakka, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244257/
https://www.ncbi.nlm.nih.gov/pubmed/25234161
http://dx.doi.org/10.1111/acel.12269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244257/
https://www.ncbi.nlm.nih.gov/pubmed/25234161
http://dx.doi.org/10.1111/acel.12269

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