Exogenous Leptin Administered Intramuscularly Induces Sex Hormone Disorder and Ca Loss via Downregulation of Gnrh and PI3K Expression

Obesity is a public health problem that increases the risk of metabolic disease, infertility, and other chronic health problems. The present study aimed to develop a new rat model for sex hormone disorder with overweight and Ca loss by intramuscular injection of exogenous leptin (LEP). Thirty female...

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Detalles Bibliográficos
Autores principales: Wu, Lihong, Liu, Wen, Bayaer, Nashun, Gu, Weiwang, Song, Jieli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2014
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244293/
https://www.ncbi.nlm.nih.gov/pubmed/25048263
http://dx.doi.org/10.1538/expanim.63.447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244293/
https://www.ncbi.nlm.nih.gov/pubmed/25048263
http://dx.doi.org/10.1538/expanim.63.447

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