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Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species

Because of the difficulty to exclude possible involvement of nuclear DNA mutations, it has been a controversial issue whether pathogenic mutations in mitochondrial DNA (mtDNA) and the resultant respiration defects are involved in tumor development. To address this issue, our previous study generated...

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Detalles Bibliográficos
Autores principales: Yamanashi, Haruka, Hashizume, Osamu, Yonekawa, Hiromichi, Nakada, Kazuto, Hayashi, Jun-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244294/
https://www.ncbi.nlm.nih.gov/pubmed/25048265
http://dx.doi.org/10.1538/expanim.63.459