Dietary restriction involves NAD(+)-dependent mechanisms and a shift toward oxidative metabolism

Interventions that slow aging and prevent chronic disease may come from an understanding of how dietary restriction (DR) increases lifespan. Mechanisms proposed to mediate DR longevity include reduced mTOR signaling, activation of the NAD(+)-dependent deacylases known as sirtuins, and increases in N...

Descripción completa

Detalles Bibliográficos
Autores principales: Moroz, Natalie, Carmona, Juan J, Anderson, Edward, Hart, Anne C, Sinclair, David A, Blackwell, T Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244309/
https://www.ncbi.nlm.nih.gov/pubmed/25257342
http://dx.doi.org/10.1111/acel.12273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244309/
https://www.ncbi.nlm.nih.gov/pubmed/25257342
http://dx.doi.org/10.1111/acel.12273

Ejemplares similares