Effects of histone deacetylase inhibitor valproic acid on skeletal myocyte development

The tight interaction between genomic DNA and histones, which normally represses gene transcription, can be relaxed by histone acetylation. This loosening of the DNA-histone complex is important for selective gene activation during stem cell differentiation. Histone acetylation may be increased thro...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qiao, Foote, Michelle, Chen, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244627/
https://www.ncbi.nlm.nih.gov/pubmed/25423891
http://dx.doi.org/10.1038/srep07207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244627/
https://www.ncbi.nlm.nih.gov/pubmed/25423891
http://dx.doi.org/10.1038/srep07207

Ejemplares similares