Targeting PPM1D by lentivirus-mediated RNA interference inhibits the tumorigenicity of bladder cancer cells

Protein phosphatase magnesium/manganese-dependent 1D (PPM1D) is a p53-induced phosphatase that functions as a negative regulator of stress response pathways and has oncogenic properties. However, the functional role of PPM1D in bladder cancer (BC) remains largely unknown. In the present study, lenti...

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Detalles Bibliográficos
Autores principales: Wang, W., Zhu, H., Zhang, H., Zhang, L., Ding, Q., Jiang, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Biomedical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244669/
https://www.ncbi.nlm.nih.gov/pubmed/25387670
http://dx.doi.org/10.1590/1414-431X20143645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244669/
https://www.ncbi.nlm.nih.gov/pubmed/25387670
http://dx.doi.org/10.1590/1414-431X20143645

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