Kinetics of Hydrogen Atom Abstraction from Substrate by an Active Site Thiyl Radical in Ribonucleotide Reductase

[Image: see text] Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms. Active E. coli class Ia RNR is an α(2)β(2) complex that undergoes reversible, long-range proton-coupled electron transfer (PCET) over a pathway of redox active amino acids...

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Detalles Bibliográficos
Autores principales: Olshansky, Lisa, Pizano, Arturo A., Wei, Yifeng, Stubbe, JoAnne, Nocera, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244835/
https://www.ncbi.nlm.nih.gov/pubmed/25353063
http://dx.doi.org/10.1021/ja507313w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244835/
https://www.ncbi.nlm.nih.gov/pubmed/25353063
http://dx.doi.org/10.1021/ja507313w

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