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Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes

BACKGROUND: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream effects on endocrine, metabolic and behavioural manifestations of PTB possibly via microRNA...

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Detalles Bibliográficos
Autores principales: Yao, Youli, Robinson, Alexandra M, Zucchi, Fabiola CR, Robbins, Jerrah C, Babenko, Olena, Kovalchuk, Olga, Kovalchuk, Igor, Olson, David M, Metz, Gerlinde AS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244860/
https://www.ncbi.nlm.nih.gov/pubmed/25286408
http://dx.doi.org/10.1186/s12916-014-0121-6