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Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes
BACKGROUND: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream effects on endocrine, metabolic and behavioural manifestations of PTB possibly via microRNA...
Autores principales: | Yao, Youli, Robinson, Alexandra M, Zucchi, Fabiola CR, Robbins, Jerrah C, Babenko, Olena, Kovalchuk, Olga, Kovalchuk, Igor, Olson, David M, Metz, Gerlinde AS |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244860/ https://www.ncbi.nlm.nih.gov/pubmed/25286408 http://dx.doi.org/10.1186/s12916-014-0121-6 |
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