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Induction of Heme Oxygenase-1 with Hemin Reduces Obesity-Induced Adipose Tissue Inflammation via Adipose Macrophage Phenotype Switching

Adipose macrophages with the anti-inflammatory M2 phenotype protect against obesity-induced inflammation and insulin resistance. Heme oxygenase-1 (HO-1), which elicits antioxidant and anti-inflammatory activity, modulates macrophage phenotypes and thus is implicated in various inflammatory diseases....

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Detalles Bibliográficos
Autores principales: Tu, Thai Hien, Joe, Yeonsoo, Choi, Hye-Seon, Chung, Hun Taeg, Yu, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244973/
https://www.ncbi.nlm.nih.gov/pubmed/25477711
http://dx.doi.org/10.1155/2014/290708