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Induction of Heme Oxygenase-1 with Hemin Reduces Obesity-Induced Adipose Tissue Inflammation via Adipose Macrophage Phenotype Switching
Adipose macrophages with the anti-inflammatory M2 phenotype protect against obesity-induced inflammation and insulin resistance. Heme oxygenase-1 (HO-1), which elicits antioxidant and anti-inflammatory activity, modulates macrophage phenotypes and thus is implicated in various inflammatory diseases....
Autores principales: | Tu, Thai Hien, Joe, Yeonsoo, Choi, Hye-Seon, Chung, Hun Taeg, Yu, Rina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244973/ https://www.ncbi.nlm.nih.gov/pubmed/25477711 http://dx.doi.org/10.1155/2014/290708 |
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