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The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression

Adipokines represent likely candidates to mediate the increased breast cancer risk and the enhanced progression associated with obesity. Other contributors to obesity-related cancer progression are insulin/IGF-1 pathways and hormones. Among these, the adipokine leptin is the most intensively studied...

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Detalles Bibliográficos
Autores principales: Andò, Sebastiano, Barone, Ines, Giordano, Cinzia, Bonofiglio, Daniela, Catalano, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245002/
https://www.ncbi.nlm.nih.gov/pubmed/25505738
http://dx.doi.org/10.3389/fonc.2014.00340