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De Novo Formation of Insulin-Producing “Neo-β Cell Islets” from Intestinal Crypts
The ability to interconvert terminally differentiated cells could serve as a powerful tool for cell-based treatment of degenerative diseases, including diabetes mellitus. To determine which, if any, adult tissues are competent to activate an islet β cell program, we performed an in vivo screen by ex...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245054/ https://www.ncbi.nlm.nih.gov/pubmed/24613355 http://dx.doi.org/10.1016/j.celrep.2014.02.013 |