De Novo Formation of Insulin-Producing “Neo-β Cell Islets” from Intestinal Crypts

The ability to interconvert terminally differentiated cells could serve as a powerful tool for cell-based treatment of degenerative diseases, including diabetes mellitus. To determine which, if any, adult tissues are competent to activate an islet β cell program, we performed an in vivo screen by ex...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ju, Finkbeiner, Stacy R., Weinblatt, Daniel, Emmett, Matthew J., Tameire, Feven, Yousefi, Maryam, Yang, Chenghua, Maehr, Rene, Zhou, Qiao, Shemer, Ruth, Dor, Yuval, Li, Changhong, Spence, Jason R., Stanger, Ben Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245054/
https://www.ncbi.nlm.nih.gov/pubmed/24613355
http://dx.doi.org/10.1016/j.celrep.2014.02.013

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