Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based Insertional Mutagenesis

Somatic cell genetics is a powerful approach for unraveling the regulatory mechanism of cholesterol metabolism. However, it is difficult to identify the mutant gene(s) due to cells are usually mutagenized chemically or physically. To identify important genes controlling cholesterol biosynthesis, an...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Tang, Jing-Jie, Miao, Hong-Hua, Qu, Yu-Xiu, Qin, Jie, Xu, Jie, Yang, Jinbo, Li, Bo-Liang, Song, Bao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245081/
https://www.ncbi.nlm.nih.gov/pubmed/25426949
http://dx.doi.org/10.1371/journal.pone.0112632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245081/
https://www.ncbi.nlm.nih.gov/pubmed/25426949
http://dx.doi.org/10.1371/journal.pone.0112632

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