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c-Met Targeting Enhances the Effect of Irradiation and Chemical Agents against Malignant Colon Cells Harboring a KRAS Mutation

Although EGFR-targeted therapy has been beneficial to colorectal cancer patients, several studies have showed this clinical benefit was restricted to patients with wild-type KRAS exon 2 colorectal cancer. Therefore, it is crucial to explore efficient treatment strategies in patients with KRAS mutati...

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Detalles Bibliográficos
Autores principales: Li, Yingbo, Wang, Jinxi, Gao, Xing, Han, Weihua, Zheng, Yongxiang, Xu, Huan, Zhang, Chuanling, He, Qiuchen, Zhang, Lihe, Li, Zhongxin, Zhou, Demin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245100/
https://www.ncbi.nlm.nih.gov/pubmed/25427200
http://dx.doi.org/10.1371/journal.pone.0113186