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Pharmacological and Behavioral Characterization of D-473, an Orally Active Triple Reuptake Inhibitor Targeting Dopamine, Serotonin and Norepinephrine Transporters

Major depressive disorder (MDD) is a debilitating disease affecting a wide cross section of people around the world. The current therapy for depression is less than adequate and there is a considerable unmet need for more efficacious treatment. Dopamine has been shown to play a significant role in d...

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Detalles Bibliográficos
Autores principales: Dutta, Aloke K., Santra, Soumava, Sharma, Horrick, Voshavar, Chandrashekhar, Xu, Liping, Mabrouk, Omar, Antonio, Tamara, Reith, Maarten E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245125/
https://www.ncbi.nlm.nih.gov/pubmed/25427177
http://dx.doi.org/10.1371/journal.pone.0113420