Influence of Nonenzymatic Posttranslational Modifications on Constitution, Oligomerization and Receptor Binding of S100A12

This study examined the effect of methylglyoxal (MGO)-derived nonenzymatic posttranslational modifications (nePTMs) on the binding affinity of S100A12 to its natural receptor for advanced glycation end-products (RAGE). Binding of MGO-modified S100A12 to RAGE decreased significantly with increasing M...

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Detalles Bibliográficos
Autores principales: Augner, Kerstin, Eichler, Jutta, Utz, Wolfgang, Pischetsrieder, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245128/
https://www.ncbi.nlm.nih.gov/pubmed/25426955
http://dx.doi.org/10.1371/journal.pone.0113418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245128/
https://www.ncbi.nlm.nih.gov/pubmed/25426955
http://dx.doi.org/10.1371/journal.pone.0113418

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