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Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism

[Image: see text] Caffeine, the most consumed psychoactive substance worldwide, may have beneficial effects on Parkinson’s disease (PD) therapy. The mechanism by which caffeine contributes to its antiparkinsonian effects by acting as either an adenosine A(2A) receptor (A(2A)R) neutral antagonist or...

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Detalles Bibliográficos
Autores principales: Fernández-Dueñas, Víctor, Gómez-Soler, Maricel, López-Cano, Marc, Taura, Jaume J., Ledent, Catherine, Watanabe, Masahiko, Jacobson, Kenneth A., Vilardaga, Jean-Pierre, Ciruela, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245165/
https://www.ncbi.nlm.nih.gov/pubmed/25268872
http://dx.doi.org/10.1021/cb5005383