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Uncovering Caffeine’s Adenosine A(2A) Receptor Inverse Agonism in Experimental Parkinsonism
[Image: see text] Caffeine, the most consumed psychoactive substance worldwide, may have beneficial effects on Parkinson’s disease (PD) therapy. The mechanism by which caffeine contributes to its antiparkinsonian effects by acting as either an adenosine A(2A) receptor (A(2A)R) neutral antagonist or...
Autores principales: | Fernández-Dueñas, Víctor, Gómez-Soler, Maricel, López-Cano, Marc, Taura, Jaume J., Ledent, Catherine, Watanabe, Masahiko, Jacobson, Kenneth A., Vilardaga, Jean-Pierre, Ciruela, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245165/ https://www.ncbi.nlm.nih.gov/pubmed/25268872 http://dx.doi.org/10.1021/cb5005383 |
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