Cargando…

Novel Imidazoline Antimicrobial Scaffold That Inhibits DNA Replication with Activity against Mycobacteria and Drug Resistant Gram-Positive Cocci

[Image: see text] Bacterial antimicrobial resistance is an escalating public health threat, yet the current antimicrobial pipeline remains alarmingly depleted, making the development of new antimicrobials an urgent need. Here, we identify a novel, potent, imidazoline antimicrobial compound, SKI-3563...

Descripción completa

Detalles Bibliográficos
Autores principales: Harris, Kendra K., Fay, Allison, Yan, Han-Guang, Kunwar, Pratima, Socci, Nicholas D., Pottabathini, Narender, Juventhala, Ramakrishna R., Djaballah, Hakim, Glickman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245167/
https://www.ncbi.nlm.nih.gov/pubmed/25222597
http://dx.doi.org/10.1021/cb500573z