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Novel Imidazoline Antimicrobial Scaffold That Inhibits DNA Replication with Activity against Mycobacteria and Drug Resistant Gram-Positive Cocci
[Image: see text] Bacterial antimicrobial resistance is an escalating public health threat, yet the current antimicrobial pipeline remains alarmingly depleted, making the development of new antimicrobials an urgent need. Here, we identify a novel, potent, imidazoline antimicrobial compound, SKI-3563...
Autores principales: | Harris, Kendra K., Fay, Allison, Yan, Han-Guang, Kunwar, Pratima, Socci, Nicholas D., Pottabathini, Narender, Juventhala, Ramakrishna R., Djaballah, Hakim, Glickman, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245167/ https://www.ncbi.nlm.nih.gov/pubmed/25222597 http://dx.doi.org/10.1021/cb500573z |
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