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General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria

[Image: see text] The chemical features that impact small-molecule permeability across bacterial membranes are poorly understood, and the resulting lack of tools to predict permeability presents a major obstacle to the discovery and development of novel antibiotics. Antibacterials are known to have...

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Detalles Bibliográficos
Autores principales: Davis, Tony D., Gerry, Christopher J., Tan, Derek S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245172/
https://www.ncbi.nlm.nih.gov/pubmed/25198656
http://dx.doi.org/10.1021/cb5003015