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(−) Arctigenin and (+) Pinoresinol Are Antagonists of the Human Thyroid Hormone Receptor β

[Image: see text] Lignans are important biologically active dietary polyphenolic compounds. Consumption of foods that are rich in lignans is associated with positive health effects. Using modeling tools to probe the ligand-binding pockets of molecular receptors, we found that lignans have high docki...

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Detalles Bibliográficos
Autores principales: Ogungbe, Ifedayo Victor, Crouch, Rebecca A., Demeritte, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245177/
https://www.ncbi.nlm.nih.gov/pubmed/25383984
http://dx.doi.org/10.1021/ci500537e