RABEX-5 Is Upregulated and Plays an Oncogenic Role in Gastric Cancer Development by Activating the VEGF Signaling Pathway

RABEX-5, a guanine-nucleotide exchange factor (GEF) for RAB-5, is implicated in tumorigenesis and in the development of certain human cancers. Here, we report that RABEX-5 promotes tumor growth and the metastatic ability of gastric cancer cells both in vitro and in vivo. Expression of RABEX-5 is sig...

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Detalles Bibliográficos
Autores principales: Wang, Shuang, Lu, Aixia, Chen, Xiangming, Wei, Lin, Ding, Jiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245226/
https://www.ncbi.nlm.nih.gov/pubmed/25427001
http://dx.doi.org/10.1371/journal.pone.0113891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245226/
https://www.ncbi.nlm.nih.gov/pubmed/25427001
http://dx.doi.org/10.1371/journal.pone.0113891

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